Major Histocompatibility Complex

mhc-ⅱ ( major histocompatibility complex class-ⅱ) molecules, constitutively expressed on the surface of mammalian cells, are critical immune regulators which responsible for presenting extracellular antigen to cd4+ t lymphocytes and activating the adaptive immune system to clear pathogen.

MHCⅡ类分子是重要的免疫调节因子，组成性表达于哺乳动物细胞表面，负责细胞外抗原的加工、呈递以活化CD4+T淋巴细胞，从而激发适应性免疫系统对外来病原体的清除。

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the present study aimed to investigate dynamic changes in tam major histocompatibility complex ( mhc) class ii expression levels and to assess the effects of these changes on tumor progression.

本研究通过小鼠肝癌模型重点探讨主要组织相容性复合体（MHC）II类分子在TAMs中表达水平的动态变化，并评估这些变化对肿瘤进展的影响。

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the doctor explained the major histocompatibility complex restriction to lily.

医生向莉莉解释了主要组织相容性复合体限制性。

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Expression of Major Histocompatibility Complex class I Antigen on Endometrial Stroma Cells in Patients with Endometriosis

子宫内膜异位症患者在位子宫内膜表面主要组织相容性复合物-Ⅰ的表达

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the expression of major histocompatibility complex in transplantable liver cancer of mouse

小鼠主要组织相容性复合体在鼠肝癌H（22）中的表达

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the apom gene is located in the major histocompatibility complex class iii region on chromosome 6.the functions of apom are to be determined.

载脂蛋白M位于6号染色体主要组织相容性抗原复合体Ⅲ区。

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advance in association studies of major histocompatibility complex ( mhc) gene polymorphisms with traits of resistance against infectious disease in chickens

鸡MHC与传染性疾病遗传抗性的相关性研究进展

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Furthermore, PSA played an important role in embryogenesis and reproduction, cellular signaling, protein transportation, regulation of major histocompatibility complex ⅰ ( MHC I) and cell cycle.

此外PSA对于细胞信号转导、蛋白质转运、主要组织相容性复合物I（MHC I）的处理、细胞周期调节、胚胎发育都有重要作用。

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it was well known that the cancer is an inherited disease. the autoimmune type 1 diabetes has been shown to be a polygenic inherited disease, with polymorphism of the major histocompatibility complex ( mhc) as the main contributor for the development of the disease.

众所周知，癌症是一种遗传疾病。自身免疫性糖尿病属多基因遗传疾病，对其遗传背景的研究主要涉及与免疫调节密切相关的主要组织相容性复合体（MHC）基因群。

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interestingly, the targets are members of the major histocompatibility complex family to which hla-g belongs.

很有趣的是，被作用的靶分子就是HLA-G所属的主要组织相容性抗原家族的一员。

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HFE gene is a major histocompatibility complex class ⅰ-like gene, which was identified as a candidate gene for hemochromatosis in 1996. The proposed role for HFE is its part in the regulation of the interaction of the transferrin receptor with transferrin.

HFE基因发现于1996年，属于HLA类样基因，是遗传性血色素沉着症候选基因。HFE分子的功能可能是参与调节转铁蛋白与转铁蛋白受体间的相互作用。

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the doctor explained the major histocompatibility gene complex to the students.

医生向学生们解释了主要组织相容性复合体。

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expression of major histocompatibility complex antigen induced by facial nerve compression

面神经损伤诱导主要组织相容性复合体抗原表达

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human leukocyte antigen ( hla), as human major histocompatibility complex, plays an important role in the genetic susceptibility to hpv infection and development of cervical cancer.

人类白细胞抗原（HLA）即人类主要组织相容性复合物（MHC），作为机体的免疫及遗传背景参与了宫颈癌的发生发展。

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dr. lee explained the function of the major histocompatibility complex gene.

李医生解释了主要组织相容性复合体基因的功能。

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The primary transcription product of nonclassical human major histocompatibility complex class I molecule HLA G is spliced to form at least seven different mRNA isoforms.

HLA G属非经典的HLA I类抗原，其初级转录产物经过不同的剪接方式形成至少7种亚型。

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relationship between major histocompatibility complex class ⅰ chain-related a and matrix metalloproteinase-9 in osteosarcoma tissue

骨肉瘤组织中主要组织相容性复合物Ⅰ类链相关A蛋白和基质金属蛋白酶-9的关系

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the researchers focused their testing on the major histocompatibility complex ( mhc), which binds to certain epitopes and is key to triggering the immune system to attack a virus-infected cell.

研究人员的研究集中在检测主要组织相容性复合物（MHC）上，它能结合特定的抗原决定簇并且它是触发免疫系统攻击感染细胞的钥匙。

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the binding of antigenic peptide sequences to major histocompatibility complex ( mhc) molecules is a prerequisite for stimulation of cytotoxic t cell responses.

抗原多肽序列与主要组织相容性复合体（MHC）分子的结合是引起T细胞免疫应答的先决条件。

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Background: HLA-G is a major histocompatibility complex ( MHC) class Ib molecule with a selective expression at the fetal-maternal interface.

研究背景HLA-G是主要组织相容复合物（MHC）Ib分子，选择性表达于母胎界面。

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conclusion: as the most important antigen presenting cells in immune response of halothane hepatitis, kupffer cells can markedly promote immune response, the antigen presenting action of kupffer cells is limited by major histocompatibility complex.

结论：Kupffer细胞是氟烷性肝炎免疫机制中重要的抗原递呈细胞，能明显促进机体免疫应答，其抗原递呈作用受MHC限制。

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Progress in Research of Canine Major Histocompatibility Complex Class ⅱ Genes

犬类MHC复合体Ⅱ类基因研究进展

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